Pacritinib (SB1518) - CD BioSciences

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Pacritinib (SB1518)

Pacritinib (SB1518)

SPC-01595

Pacritinib (SB1518)

CAS No. 937272-79-2

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JAK inhibitor ; FLT3 inhibitor

Description
Pacritinib (SB1518) is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays, respectively. Phase 3.
Product Details
CAS No. CAS No. 937272-79-2
Description Pacritinib (SB1518) is a potent and selective inhibitor of Janus Kinase 2 (JAK2) and Fms-Like Tyrosine Kinase-3 (FLT3) with IC50s of 23 and 22 nM in cell-free assays, respectively. Phase 3.
Formula C28H32N4O3
Molecular Weight 472.58
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1CCN(C1)CCOC2=C3COCC=CCOCC4=CC(=CC=C4)C5=NC(=NC=C5)NC(=C3)C=C2
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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