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OX40/TNFRSF4 Antibody
SPA-10963
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | TNF receptor |
| Gene Abbr. | TNFRSF4 |
| Gene ID | 7293 |
| Full Name | TNF receptor superfamily member 4 |
| Alias | ACT35, CD134, IMD16, OX40, TXGP1L |
| Introduction | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
| Product Details | |
|---|---|
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | 443318 |
| Isotype | IgG2A |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant human OX40/TNFRSF4. Leu29-Ala216. Accession # P43489. |
| Usage | |
|---|---|
| Application | WB, FC |
| Dilutions | Western Blot (1 µg/mL); Flow Cytometry (0.25 µg/10^6 cells) |
| Reactivity | Human |
| Specificity | Detects human OX40/TNFRSF4 in direct ELISAs and Western Blots. In Western Blots, no cross-reactivity with recombinant human (rh) 4-1BB, rhBAFF R, rhCD27, rhCD30, rhCD40, rhDR3, rhDR6, rhEDAR, rhFAS, rhGITR, rhHVEM, rhLT beta R, rhNGF R, rhRANK, rhRELT, rhTAJ, rhTNF RI, rhTNF RII, rhTRAIL, rhTRAIL R4, rhTRAIL R3, rhTWEAK R, or rhXEDAR is observed. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.