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Osteoprotegerin/TNFRSF11B Antibody
SPA-10830
| Size | Price |
| 0.025 mg | Online Inquiry |
| 0.1 mg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | TNF receptor |
| Gene Abbr. | TNFRSF11B |
| Gene ID | 4982 |
| Full Name | TNF receptor superfamily member 11b |
| Alias | OCIF, OPG, PDB5, TR1 |
| Introduction | The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. [provided by RefSeq] |
| Product Details | |
|---|---|
| Host | Rat |
| Clonality | Monoclonal |
| Clone No. | 110511 |
| Isotype | IgG2A |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse Osteoprotegerin/TNFRSF11B. Gln21-Leu401 (Gln138Arg). Accession # Q6PI12. |
| Usage | |
|---|---|
| Application | WB, ELISA |
| Dilutions | Western Blot (1 µg/mL); ELISA Capture (2-8 µg/mL); ELISA Detection (0.1-0.4 µg/mL) |
| Reactivity | Mouse |
| Specificity | Detects mouse Osteoprotegerin/TNFRSF11B in ELISAs and Western Blots. In Western Blots, this antibody shows 100% cross-reactivity with recombinant human (rh) Osteoprotegerin and no cross-reactivity with rh4-1BB, recombinant mouse (rm) CD27, rmCD40, rhDR3, rhDR6, rmFas, rmGITR, rhHVEM, rhLT beta R, rmRANK, rmTNF RI, or rmTNF RII. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. |
| Preservative | No Preservative |
| Storage Temp. | 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution. |
| Handling | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.