Osimertinib (AZD9291) - CD BioSciences

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Osimertinib (AZD9291)

Osimertinib (AZD9291)

SPC-01572

Osimertinib (AZD9291)

CAS No. 1421373-65-0

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EGFR inhibitor

Description
Osimertinib (AZD9291) is an oral, irreversible, and mutant-selective EGFR inhibitor with IC50 of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR in LoVo cells, respectively. Phase 3.
Product Details
CAS No. CAS No. 1421373-65-0
Description Osimertinib (AZD9291) is an oral, irreversible, and mutant-selective EGFR inhibitor with IC50 of 12.92, 11.44 and 493.8 nM for Exon 19 deletion EGFR, L858R/T790M EGFR, and WT EGFR in LoVo cells, respectively. Phase 3.
Formula C28 H33 N7 O2
Molecular Weight 499.61
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CN1C=C(C2=CC=CC=C21)C3=NC(=NC=C3)NC4=C(C=C(C(=C4)NC(=O)C=C)N(C)CCN(C)C)OC
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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