OSI-930 - CD BioSciences

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OSI-930

OSI-930

SPC-01571

OSI-930

CAS No. 728033-96-3

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10 mM (1 mL in DMSO) Online Inquiry
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c-Kit inhibitor ; CSF-1R inhibitor ; VEGFR inhibitor

Description
OSI-930 is a potent inhibitor of Kit, KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.
Product Details
CAS No. CAS No. 728033-96-3
Description OSI-930 is a potent inhibitor of Kit, KDR and CSF-1R with IC50 of 80 nM, 9 nM and 15 nM, respectively; also potent to Flt-1, c-Raf and Lck and low activity against PDGFRα/β, Flt-3 and Abl. Phase 1.
Formula C22H16F3N3O2S
Molecular Weight 443.44
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1=CC=C2C(=C1)C(=CC=N2)CNC3=C(SC=C3)C(=O)NC4=CC=C(C=C4)OC(F)(F)F
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.