Online Inquiry
Omipalisib (GSK2126458)
SPC-01549
CAS No. 1086062-66-9
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 2 mg | Online Inquiry |
| 5 mg | Online Inquiry |
| 10 mg | Online Inquiry |
| 50 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
PI3K inhibitor ; mTOR inhibitor ; Autophagy activator
| Description |
|---|
| Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Omipalisib induces autophagy. Phase 1. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 1086062-66-9 |
| Description | Omipalisib (GSK2126458, GSK458) is a highly selective and potent inhibitor of p110α/β/δ/γ, mTORC1/2 with Ki of 0.019 nM/0.13 nM/0.024 nM/0.06 nM and 0.18 nM/0.3 nM in cell-free assays, respectively. Omipalisib induces autophagy. Phase 1. |
| Formula | C25H17F2N5O3S |
| Molecular Weight | 505.5 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | GSK458 |
| SMILES | COC1=C(C=C(C=N1)C2=CC3=C(C=CN=C3C=C2)C4=CN=NC=C4)NS(=O)(=O)C5=C(C=C(C=C5)F)F |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.