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NVP-CGM097
SPC-01530
CAS No. 1313363-54-0
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5 mg | Online Inquiry |
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Mdm2 inhibitor
Description |
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NVP-CGM097 is a highly potent and selective MDM2 inhibitor with Ki value of 1.3 nM for hMDM2 in TR-FRET assay. It binds to the p53 binding-site of the Mdm2 protein, disrupting the interaction between both proteins, leading to an activation of the p53 pathway. |
Product Details | |
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CAS No. | CAS No. 1313363-54-0 |
Description | NVP-CGM097 is a highly potent and selective MDM2 inhibitor with Ki value of 1.3 nM for hMDM2 in TR-FRET assay. It binds to the p53 binding-site of the Mdm2 protein, disrupting the interaction between both proteins, leading to an activation of the p53 pathway. |
Formula | C38H47ClN4O4 |
Molecular Weight | 659.26 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | CGM-097, CGM 097, CGM 097, NVP CGM097 |
SMILES | CC(C)OC1=C(C=C2CC(=O)N(C(C2=C1)C3=CC=C(C=C3)Cl)C4=CC=C(C=C4)N(C)CC5CCC(CC5)N6CCN(C(=O)C6)C)OC |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.