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Nutlin-3a
SPC-01521
CAS No. 675576-98-4
| Size | Price |
| 5 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Mdm2 inhibitor ; p53 inhibitor ; Autophagy activator ; Apoptosis related activator
| Description |
|---|
| Nutlin-3a, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 675576-98-4 |
| Description | Nutlin-3a, the active enantiomer of Nutlin-3, inhibits the p53/MDM2 interaction with IC50 of 90 nM in a cell-free assay. Nutlin-3a induces autophagy and apoptosis in a p53-dependent manner. |
| Formula | C30H30Cl2N4O4 |
| Molecular Weight | 581.49 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | (-)-Nutlin-3 |
| SMILES | CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.