NMS-P118 - CD BioSciences

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NMS-P118

NMS-P118

SPC-01495

NMS-P118

CAS No. 1262417-51-5

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PARP inhibitor

Description
NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively).
Product Details
CAS No. CAS No. 1262417-51-5
Description NMS-P118 is a potent, orally available, and highly selective PARP-1 inhibitor endowed with excellent ADME and pharmacokinetic profiles, showing 150-fold selectivity for PARP-1 over PARP-2 (Kd 0.009 μM vs 1.39 μM, respectively).
Formula C20H24F3N3O2
Molecular Weight 395.42
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1CC(CCC1N2CCC(CC2)N3CC4=C(C3=O)C(=CC(=C4)F)C(=O)N)(F)F
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.