Niraparib (MK-4827) tosylate - CD BioSciences

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Niraparib (MK-4827) tosylate

Niraparib (MK-4827) tosylate

SPC-01487

Niraparib (MK-4827) tosylate

CAS No. 1038915-73-9

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PARP inhibitor ; Apoptosis related activator

Description
Niraparib tosylate (MK-4827, ZEJULA) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death.
Product Details
CAS No. CAS No. 1038915-73-9
Description Niraparib tosylate (MK-4827, ZEJULA) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death.
Formula C19H20N4O.C7H8O3S
Molecular Weight 492.59
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms Niraparib tosylate, MK 4827 tosylate, ZEJULA
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.C1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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