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Niraparib (MK-4827) tosylate
SPC-01487
CAS No. 1038915-73-9
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PARP inhibitor ; Apoptosis related activator
Description |
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Niraparib tosylate (MK-4827, ZEJULA) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death. |
Product Details | |
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CAS No. | CAS No. 1038915-73-9 |
Description | Niraparib tosylate (MK-4827, ZEJULA) is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM. Niraparib increases formation of PARP-DNA complexes resulting in DNA damage, apoptosis, and cell death. |
Formula | C19H20N4O.C7H8O3S |
Molecular Weight | 492.59 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | Niraparib tosylate, MK 4827 tosylate, ZEJULA |
SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.C1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.