Nilotinib (AMN-107) - CD BioSciences

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Nilotinib (AMN-107)

Nilotinib (AMN-107)

SPC-01479

Nilotinib (AMN-107)

CAS No. 641571-10-0

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10 mM (1 mL in DMSO) Online Inquiry
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Bcr-Abl inhibitor ; Autophagy activator ; AMPK activator

Description
Nilotinib (AMN-107) is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.
Product Details
CAS No. CAS No. 641571-10-0
Description Nilotinib (AMN-107) is a selective Bcr-Abl inhibitor with IC50 less than 30 nM in Murine myeloid progenitor cells. Nilotinib induces autophagy through AMPK activition.
Formula C28H22F3N7O
Molecular Weight 529.52
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)C(F)(F)F)N3C=C(N=C3)C)NC4=NC=CC(=N4)C5=CN=CC=C5
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.