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Niclosamide
SPC-01473
CAS No. 50-65-7
| Size | Price |
| 50 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
STAT inhibitor ; Autophagy activator
| Description |
|---|
| Niclosamide (Niclocide) can inhibit DNA replication and inhibit STAT3 with IC50 of 0.7 μM in a cell-free assay. Niclosamide selectively inhibited the phosphorylation of STAT3 and had no obvious inhibition against the activation of other homologues (e.g., STAT1 and STAT5). |
| Product Details | |
|---|---|
| CAS No. | CAS No. 50-65-7 |
| Description | Niclosamide (Niclocide) can inhibit DNA replication and inhibit STAT3 with IC50 of 0.7 μM in a cell-free assay. Niclosamide selectively inhibited the phosphorylation of STAT3 and had no obvious inhibition against the activation of other homologues (e.g., STAT1 and STAT5). |
| Formula | C13H8Cl2N2O4 |
| Molecular Weight | 327.12 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Niclocide |
| SMILES | C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.