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Necrostatin-1
SPC-01459
CAS No. 4311-88-0
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 10 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
RIP kinase inhibitor ; TNF-alpha inhibitor ; IDO/TDO inhibitor ; Autophagy inhibitor ; Apoptosis related inhibitor
| Description |
|---|
| Necrostatin-1 is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells. Necrostatin-1 also blocks IDO and suppresses autophagy and apoptosis. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 4311-88-0 |
| Description | Necrostatin-1 is a specific RIP1 (RIPK1) inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM in 293T cells. Necrostatin-1 also blocks IDO and suppresses autophagy and apoptosis. |
| Formula | C13H13N3OS |
| Molecular Weight | 259.33 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | N/A |
| SMILES | CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32 |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.