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Nazartinib (EGF816)
SPC-01454
CAS No. 1508250-71-2
| Size | Price |
| 5 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
EGFR inhibitor
| Description |
|---|
| Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 1508250-71-2 |
| Description | Nazartinib (EGF816, NVS-816) is a covalent, irreversible, mutant-selective EGFR inhibitor that has nanomolar inhibitory potency against activating mt (L858R, ex19del) and T790M mt, with up to 60-fold selectivity over wild type (wt) EGFR in vitro. |
| Formula | C26H31ClN6O2 |
| Molecular Weight | 495.02 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | NVS-816 |
| SMILES | CC1=NC=CC(=C1)C(=O)NC2=NC3=C(N2C4CCCCN(C4)C(=O)C=CCN(C)C)C(=CC=C3)Cl |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.