Mocetinostat (MGCD0103) - CD BioSciences

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Mocetinostat (MGCD0103)

Mocetinostat (MGCD0103)

SPC-01403

Mocetinostat (MGCD0103)

CAS No. 726169-73-9

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10 mM (1 mL in DMSO) Online Inquiry
5 mg Online Inquiry
10 mg Online Inquiry
25 mg Online Inquiry
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HDAC inhibitor ; Apoptosis related activator ; Autophagy activator

Description
Mocetinostat (MGCD0103, MG0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM in a cell-free assay, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Mocetinostat (MGCD0103) induces apoptosis and autophagy. Phase 2.
Product Details
CAS No. CAS No. 726169-73-9
Description Mocetinostat (MGCD0103, MG0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM in a cell-free assay, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Mocetinostat (MGCD0103) induces apoptosis and autophagy. Phase 2.
Formula C23H20N6O
Molecular Weight 396.44
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms MG0103
SMILES C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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