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Mocetinostat (MGCD0103)
SPC-01403
CAS No. 726169-73-9
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
5 mg | Online Inquiry |
10 mg | Online Inquiry |
25 mg | Online Inquiry |
Bulk Size | Online Inquiry |
HDAC inhibitor ; Apoptosis related activator ; Autophagy activator
Description |
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Mocetinostat (MGCD0103, MG0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM in a cell-free assay, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Mocetinostat (MGCD0103) induces apoptosis and autophagy. Phase 2. |
Product Details | |
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CAS No. | CAS No. 726169-73-9 |
Description | Mocetinostat (MGCD0103, MG0103) is a potent HDAC inhibitor with most potency for HDAC1 with IC50 of 0.15 μM in a cell-free assay, 2- to 10- fold selectivity against HDAC2, 3, and 11, and no activity to HDAC4, 5, 6, 7, and 8. Mocetinostat (MGCD0103) induces apoptosis and autophagy. Phase 2. |
Formula | C23H20N6O |
Molecular Weight | 396.44 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | MG0103 |
SMILES | C1=CC=C(C(=C1)N)NC(=O)C2=CC=C(C=C2)CNC3=NC=CC(=N3)C4=CN=CC=C4 |
Solubility | DMSO |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.