ML347 - CD BioSciences

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ML347

ML347

SPC-01396

ML347

CAS No. 1062368-49-3

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TGF-beta/Smad inhibitor

Description
ML347 (LDN-193719) is a selective BMP receptor inhibitor with IC50 of 32 nM for ALK2, >300-fold selectivity over ALK3. Also inhibits ALK1 activity with IC50 of 46 nM.
Product Details
CAS No. CAS No. 1062368-49-3
Description ML347 (LDN-193719) is a selective BMP receptor inhibitor with IC50 of 32 nM for ALK2, >300-fold selectivity over ALK3. Also inhibits ALK1 activity with IC50 of 46 nM.
Formula C22 H16 N4 O
Molecular Weight 352.39
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms LDN-193719
SMILES COC1=CC=C(C=C1)C2=CN3C(=C(C=N3)C4=C5C=CC=NC5=CC=C4)N=C2
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.