MK-8617 - CD BioSciences

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MK-8617

MK-8617

SPC-01386

MK-8617

CAS No. 1187990-87-9

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HIF modulator

Description
MK-8617 is an orally active pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3), inhibiting PHD1, 2, 3 with IC50s of 1.0, 1.0 and 14 nM, respectively.
Product Details
CAS No. CAS No. 1187990-87-9
Description MK-8617 is an orally active pan-inhibitor of Hypoxia-inducible factor prolyl hydroxylase 1−3 (HIF PHD1−3), inhibiting PHD1, 2, 3 with IC50s of 1.0, 1.0 and 14 nM, respectively.
Formula C24H21N5O4
Molecular Weight 443.45
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES COC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC)NC(=O)C3=CN=C(NC3=O)C4=NN=CC=C4
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.