MK-2206 2HCl - CD BioSciences

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MK-2206 2HCl

MK-2206 2HCl

SPC-01381

MK-2206 2HCl

CAS No. 1032350-13-2

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10 mM (1 mL in DMSO) Online Inquiry
5 mg Online Inquiry
10 mg Online Inquiry
25 mg Online Inquiry
50 mg Online Inquiry
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Akt inhibitor ; Autophagy activator ; Apoptosis related activator

Description
MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. MK-2206 2HCl induces autophagy and apoptosis in cancer cells. Phase 2.
Product Details
CAS No. CAS No. 1032350-13-2
Description MK-2206 2HCl is a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM in cell-free assays, respectively; no inhibitory activities against 250 other protein kinases observed. MK-2206 2HCl induces autophagy and apoptosis in cancer cells. Phase 2.
Formula C25H21N5O.2HCl
Molecular Weight 480.39
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1CC(C1)(C2=CC=C(C=C2)C3=C(C=C4C(=N3)C=CN5C4=NNC5=O)C6=CC=CC=C6)N.Cl.Cl
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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