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Mitoxantrone 2HCl
SPC-01377
CAS No. 70476-82-3
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 50 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Topoisomerase inhibitor ; COVID-19 inhibitor ; Apoptosis related activator ; PKC inhibitor
| Description |
|---|
| Mitoxantrone 2HCl (NSC-301739) is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 70476-82-3 |
| Description | Mitoxantrone 2HCl (NSC-301739) is a dihydrochloride salt of Mitoxantrone. Mitoxantrone is an inhibitor of type II topoisomerase and protein kinase C (PKC) with IC50 of 8.5 μM for PKC. Mitoxantrone inhibits cell proliferative growth of MCF-7/wt cells with IC50 of 0.42 μM. Mitoxantrone also induces apoptosis. |
| Formula | C22H29ClN4O6.2HCl |
| Molecular Weight | 517.4 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | NSC-301739 |
| SMILES | C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.