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MITF Antibody
SPA-07603
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | MITF |
| Gene Abbr. | MITF |
| Gene ID | 4286 |
| Full Name | melanocyte inducing transcription factor |
| Alias | CMM8, COMMAD, MI, WS2, WS2A |
| Introduction | Microphthalmia-associated transcription factor (MITF) is a basic helix-loop-helix leucine zipper transcription factor that is most widely known for its roles in melanocyte, ophthalmic, and osteoclast development. In humans, MITF can function as a melanoma oncogene and mutations in the corresponding MITF gene are associated with Waardenburg syndrome type 2, an auditory-pigmentary syndrome characterized by developmental defects in cells derived from neural crest. At least 12 isoforms of MITF have been identified, which exhibit differential patterns of expression among cell and tissue types. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | D3B4T |
| Immunogen | Recombinant protein specific to the carboxy terminus of human MITF protein. |
| Source/Purification | Antibody is produced by immunizing animals with recombinant protein specific to the carboxy terminus of human MITF protein. |
| Usage | |
|---|---|
| Application | WB, IP, ChIP |
| Dilutions | Western Blot (1:1000) |
| MW(KDa) | 50-75 |
| Reactivity | Human, Mouse, Monkey |
| Sensitivity | Endogenous |
| Specificity | It recognizes endogenous levels of total MITF protein. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.