Mirdametinib (PD0325901) - CD BioSciences

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Mirdametinib (PD0325901)

Mirdametinib (PD0325901)

SPC-01373

Mirdametinib (PD0325901)

CAS No. 391210-10-9

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MEK inhibitor

Description
Mirdametinib (PD0325901) is a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM in cell-free assays, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2. Phase 2.
Product Details
CAS No. CAS No. 391210-10-9
Description Mirdametinib (PD0325901) is a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM in cell-free assays, roughly 500-fold more potent than CI-1040 on phosphorylation of ERK1 and ERK2. Phase 2.
Formula C16H14F3IN2O4
Molecular Weight 482.19
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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