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Mifepristone
SPC-01362
CAS No. 84371-65-3
| Size | Price |
| 10 mM (1 mL in DMSO) | Online Inquiry |
| 50 mg | Online Inquiry |
| 200 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Estrogen/progestogen Receptor antagonist ; Glucocorticoid Receptor antagonist ; Bcl-2 inhibitor ; Autophagy activator ; Apoptosis related activator
| Description |
|---|
| Mifepristone (RU486, C-1073) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 84371-65-3 |
| Description | Mifepristone (RU486, C-1073) is a remarkably active antagonist of progesterone receptor and glucocorticoid receptor with IC50 of 0.2 nM and 2.6 nM, respectively. Mifepristone promotes cell autophagy and apoptosis, decreases Bcl-2 level and increases Beclin1 level, accompanied by weakened interaction between Bcl-2 and Beclin1. |
| Formula | C29H35NO2 |
| Molecular Weight | 429.59 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | RU486, C-1073 |
| SMILES | CC#CC1(CCC2C1(CC(C3=C4CCC(=O)C=C4CCC23)C5=CC=C(C=C5)N(C)C)C)O |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.