Online Inquiry
MICAL1 Antibody
SPA-07574
| Size | Price |
| 25 µg | Online Inquiry |
| 100 µg | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | MICAL1 |
| Gene Abbr. | MICAL1 |
| Gene ID | 64780 |
| Full Name | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| Alias | MICAL, MICAL-1, NICAL |
| Introduction | Molecule interacting with CasL protein 1 (MICAL1) is a Protein-methionine sulfoxide oxidase. MICAL1 can bind directly to F-actin and oxidize specific methionine residues to promote actin filament disassembly. MICAL1 is an important component of semaphorin signaling cascades that has effects on cell movement, angiogenesis, immunology, diabetes, and cancer. MICAL1 binds to NDR1/2 and antagonizes MST1-induced NDR activation and apoptosis. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Monoclonal |
| Clone No. | D8K7R |
| Immunogen | Synthetic peptide corresponding to residues surrounding Val1038 of human MICAL1 protein. |
| Source/Purification | Antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Val1038 of human MICAL1 protein. |
| Usage | |
|---|---|
| Application | WB, IP |
| Dilutions | Western Blot (1:1000); Immunoprecipitation (1:200) |
| MW(KDa) | 130 |
| Reactivity | Human |
| Sensitivity | Endogenous |
| Specificity | It recognizes endogenous levels of total MICAL1 protein. |
| Storage & Handling | |
|---|---|
| Storage Buffer | Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide. |
| Preservative | Less than 0.02% Sodium Azide |
| Storage Temp. | Store at -20 °C. |
| Handling | Do not aliquot the antibody. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.