MGCD-265 analog - CD BioSciences

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MGCD-265 analog

MGCD-265 analog

SPC-01355

MGCD-265 analog

CAS No. 875337-44-3

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10 mM (1 mL in DMSO) Online Inquiry
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c-Met inhibitor ; Tie-2 inhibitor ; VEGFR inhibitor

Description
MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.
Product Details
CAS No. CAS No. 875337-44-3
Description MGCD-265 is a potent, multi-target and ATP-competitive inhibitor of c-Met and VEGFR1/2/3 with IC50 of 1 nM, 3 nM/3 nM/4 nM, respectively; also inhibits Ron and Tie2. Phase 1/2.
Formula C26H20FN5O2S2
Molecular Weight 517.60
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CN1C=C(N=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=CC=C5)F
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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