LY364947 - CD BioSciences

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LY364947

LY364947

SPC-01291

LY364947

CAS No. 396129-53-6

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TGF-beta/Smad inhibitor ; RIP kinase inhibitor ; Casein Kinase inhibitor ; Mixed Lineage Kinase inhibitor

Description
LY364947 (HTS 466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM in a cell-free assay, shows 7-fold selectivity over TGFβR-II.
Product Details
CAS No. CAS No. 396129-53-6
Description LY364947 (HTS 466284) is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM in a cell-free assay, shows 7-fold selectivity over TGFβR-II.
Formula C17H12N4
Molecular Weight 272.3
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms HTS 466284
SMILES C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.