LY 3200882 - CD BioSciences

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LY 3200882

LY 3200882

SPC-01276

LY 3200882

CAS No. 1898283-02-7

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TGF-beta/Smad inhibitor

Description
LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.
Product Details
CAS No. CAS No. 1898283-02-7
Description LY 3200882 is a potent, highly selective inhibitor of TGF-β receptor type 1 (TGFβRI). It potently inhibits TGFβ mediated SMAD phosphorylation in vitro in tumor and immune cells and in vivo in subcutaneous tumors in a dose dependent fashion.
Formula C24H29N5O3
Molecular Weight 435.52
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC(C)(C1=NC=CC(=C1)NC2=NC=CC(=C2)OC3=CN(N=C3C4CCOCC4)C5CC5)O
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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