Losmapimod (GW856553X) - CD BioSciences

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Losmapimod (GW856553X)

Losmapimod (GW856553X)

SPC-01261

Losmapimod (GW856553X)

CAS No. 585543-15-3

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p38 MAPK inhibitor ; Apoptosis related activator ; Autophagy activator

Description
Losmapimod (GW856553X) is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. P38 MAPKs are involved in cell differentiation, apoptosis and autophagy. Phase 3.
Product Details
CAS No. CAS No. 585543-15-3
Description Losmapimod (GW856553X) is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. P38 MAPKs are involved in cell differentiation, apoptosis and autophagy. Phase 3.
Formula C22 H26 F N3 O2
Molecular Weight 383.46
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms GW856553, GSK-AHAB
SMILES CC1=C(C=C(C=C1F)C(=O)NC2CC2)C3=NC=C(C=C3)C(=O)NCC(C)(C)C
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.