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Losmapimod (GW856553X)
SPC-01261

CAS No. 585543-15-3
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10 mg | Online Inquiry |
50 mg | Online Inquiry |
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p38 MAPK inhibitor ; Apoptosis related activator ; Autophagy activator
Description |
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Losmapimod (GW856553X) is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. P38 MAPKs are involved in cell differentiation, apoptosis and autophagy. Phase 3. |
Product Details | |
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CAS No. | CAS No. 585543-15-3 |
Description | Losmapimod (GW856553X) is a selective, potent, and orally active p38 MAPK inhibitor with pKi of 8.1 and 7.6 for p38α and p38β, respectively. P38 MAPKs are involved in cell differentiation, apoptosis and autophagy. Phase 3. |
Formula | C22 H26 F N3 O2 |
Molecular Weight | 383.46 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | GW856553, GSK-AHAB |
SMILES | CC1=C(C=C(C=C1F)C(=O)NC2CC2)C3=NC=C(C=C3)C(=O)NCC(C)(C)C |
Usage | |
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Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.