Linsitinib (OSI-906) - CD BioSciences

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Linsitinib (OSI-906)

Linsitinib (OSI-906)

SPC-01244

Linsitinib (OSI-906)

CAS No. 867160-71-2

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10 mM (1 mL in DMSO) Online Inquiry
10 mg Online Inquiry
50 mg Online Inquiry
Bulk Size Online Inquiry

IGF-1R inhibitor

Description
Linsitinib (OSI-906) is a selective inhibitor of IGF-1R with IC50 of 35 nM in cell-free assays; modestly potent to InsR with IC50 of 75 nM, and no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc. Phase 3.
Product Details
CAS No. CAS No. 867160-71-2
Description Linsitinib (OSI-906) is a selective inhibitor of IGF-1R with IC50 of 35 nM in cell-free assays; modestly potent to InsR with IC50 of 75 nM, and no activity towards Abl, ALK, BTK, EGFR, FGFR1/2, PKA etc. Phase 3.
Formula C26H23N5O
Molecular Weight 421.49
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES CC1(CC(C1)C2=NC(=C3N2C=CN=C3N)C4=CC5=C(C=C4)C=CC(=N5)C6=CC=CC=C6)O
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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