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Lifirafenib (BGB-283)
SPC-01240
CAS No. 1446090-79-4
| Size | Price |
| 5 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Raf inhibitor ; EGFR inhibitor
| Description |
|---|
| Lifirafenib (BGB-283, Beigene-283) potently inhibits RAF family kinases and EGFR activities in biochemical assays with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 1446090-79-4 |
| Description | Lifirafenib (BGB-283, Beigene-283) potently inhibits RAF family kinases and EGFR activities in biochemical assays with IC50 values of 23, 29 and 495 nM for the recombinant BRAFV600E kinase domain, EGFR and EGFR T790M/L858R mutant. |
| Formula | C25H17F3N4O3 |
| Molecular Weight | 478.42 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | Beigene-283 |
| SMILES | C1CC(=O)NC2=NC=CC(=C21)OC3=CC4=C(C=C3)OC5C4C5C6=NC7=C(N6)C=C(C=C7)C(F)(F)F |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.