Leptin Sandwich ELISA Kit - CD BioSciences

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Leptin Sandwich ELISA Kit

Leptin Sandwich ELISA Kit

SPK-00794

Size Price
1 X 96T Online Inquiry
5 X 96T Online Inquiry
10 X 96T Online Inquiry
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Target Information
Target Name Leptin
Gene Abbr. Lep
Gene ID 25608
Full Name leptin
Alias OB, obese
Introduction Leptin, the obese (ob) gene product, is a small protein expressed in and secreted from adipose tissue of normal rodents. Studies suggest leptin acts as a circulating hormone capable of regulating body-weight homeostasis and energy balance. One possible target tissue for leptin is the hypothalamus, a proposed control center for satiety and energy expenditure. Ob gene knockout mice are characterized by several metabolic abnormalities including hyperglucocorticoidemia, hyperinsulinemia and insulin resistance, hyperglycemia, altered central nervous system activity, reduced metabolic rate of brown adipose tissue, and a large increase in white adipose tissue. Studies show that the administration of recombinant leptin to ob knockout mice reduces food intake and increases energy expenditure.
Product Details
Measurement Sandwich
Usage
Application ELISA
Reactivity
Assay Principle quantitative
Sensitivity 0.068 ng/mL
Detection Range 0.068 ng/mL - 50 ng/mL
Sample Volume 50-100μL
Assay Time 1-5h
Detection Wavelength 450 nm
Storage & Handling
Storage Temp. Store at 2-8°C. Please refer to protocol.

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