LDN-212854 - CD BioSciences

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LDN-212854

LDN-212854

SPC-01215

LDN-212854

CAS No. 1432597-26-6

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TGF-beta/Smad inhibitor

Description
LDN-212854 is a potent and selective BMP receptor inhibitor with IC50 of 1.3 nM for ALK2, about 2-, 66-, 1641-, and 7135-fold selectivity over ALK1, ALK3, ALK4, and ALK5, respectively.
Product Details
CAS No. CAS No. 1432597-26-6
Description LDN-212854 is a potent and selective BMP receptor inhibitor with IC50 of 1.3 nM for ALK2, about 2-, 66-, 1641-, and 7135-fold selectivity over ALK1, ALK3, ALK4, and ALK5, respectively.
Formula C25 H22 N6
Molecular Weight 406.48
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms BMP Inhibitor III
SMILES C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=C6C=CC=NC6=CC=C5)N=C3
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.