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LDN-193189
SPC-01213
CAS No. 1062368-24-4
| Size | Price |
| 2 mg | Online Inquiry |
| 5 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
TGF-beta/Smad inhibitor
| Description |
|---|
| LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 1062368-24-4 |
| Description | LDN-193189 (DM3189) is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cells, respectively, exhibits 200-fold selectivity for BMP versus TGF-β. |
| Formula | C25H22N6 |
| Molecular Weight | 406.48 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | DM3189 |
| SMILES | C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=CC=NC6=CC=CC=C56)N=C3 |
| Solubility | DMSO |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.