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Larotrectinib (LOXO-101) sulfate
SPC-01203
CAS No. 1223405-08-0
| Size | Price |
| 5 mg | Online Inquiry |
| 25 mg | Online Inquiry |
| 100 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Trk receptor inhibitor ; Apoptosis related activator
| Description |
|---|
| Larotrectinib (LOXO-101) sulfate is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 1223405-08-0 |
| Description | Larotrectinib (LOXO-101) sulfate is an oral potent and selective ATP-competitive inhibitor of tropomyosin receptor kinases (TRK). Larotrectinib inhibition of TRKs induces cellular apoptosis and G1 cell-cycle arrest. |
| Formula | C21H22F2N6O2.H2SO4 |
| Molecular Weight | 526.51 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | ARRY-470, Larotrectinib |
| SMILES | C1CC(N(C1)C2=NC3=C(C=NN3C=C2)NC(=O)N4CCC(C4)O)C5=C(C=CC(=C5)F)F.OS(=O)(=O)O |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.