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LAMTOR2/ROBLD3 Antibody
SPA-06899
| Size | Price |
| 0.05 mL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | LAMTOR2 |
| Gene Abbr. | LAMTOR2 |
| Gene ID | 28956 |
| Full Name | late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 |
| Alias | ENDAP, HSPC003, MAPBPIP, MAPKSP1AP, ROBLD3 |
| Introduction | mTORC1 kinase complex is a critical component in the regulation of cell growth. Its activity is modulated by energy levels, growth factors, and amino acids. The four related GTPases, RagA, RagB, RagC, and RagD, have been shown to interact with raptor in mTORC1. These interactions are both necessary and sufficient for mTORC1 activation in response to amino acid signals. A protein complex consisting of LAMTOR1/C11orf59, LAMTOR2/ROBLD3, and LAMTOR3/MAPKSP1 has been identified to interact with and recruit the four Rag GTPases to the surface of lysosomes. |
| Product Details | |
|---|---|
| Host | Rabbit |
| Clonality | Polyclonal |
| Clone No. | N/A |
| Isotype | IgG |
| Immunogen | A genomic peptide made to an N-terminal region of the human ROBLD3 protein (within residues 1-125). [Swiss-Prot Q9Y2Q5]. |
| Usage | |
|---|---|
| Application | IF, IHC |
| Dilutions | Immunofluorescence (1:50-1:100); Immunohistochemistry (1:100-1:200) |
| MW(KDa) | 14 |
| Reactivity | Human, Mouse |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS, 0.1% BSA, and 50% Glycerol. |
| Preservative | 0.05% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.