KW-2449 - CD BioSciences

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KW-2449

KW-2449

SPC-01183

KW-2449

CAS No. 1000669-72-6

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10 mM (1 mL in DMSO) Online Inquiry
10 mg Online Inquiry
25 mg Online Inquiry
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FLT3 inhibitor ; Aurora Kinase inhibitor ; Bcr-Abl inhibitor

Description
KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC50 of 6.6 nM, modestly potent to FGFR1, Bcr-Abl and Aurora A; little effect on PDGFRβ, IGF-1R, EGFR. Phase 1.
Product Details
CAS No. CAS No. 1000669-72-6
Description KW-2449 is a multiple-targeted inhibitor, mostly for Flt3 with IC50 of 6.6 nM, modestly potent to FGFR1, Bcr-Abl and Aurora A; little effect on PDGFRβ, IGF-1R, EGFR. Phase 1.
Formula C20H20N4O
Molecular Weight 332.4
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms N/A
SMILES C1CN(CCN1)C(=O)C2=CC=C(C=C2)C=CC3=NNC4=CC=CC=C43
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.