JANEX-1 - CD BioSciences

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JANEX-1

JANEX-1

SPC-01133

JANEX-1

CAS No. 202475-60-3

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JAK inhibitor

Description
JANEX-1 (WHI-P131) is a small molecule inhibitor of JAK3 that selectively inhibits JAK3 at an IC50 of 78 µM without altering the activity of JAK1 or JAK2, or any other protein tyrosine kinases (IC50 ≥ 350 µM).
Product Details
CAS No. CAS No. 202475-60-3
Description JANEX-1 (WHI-P131) is a small molecule inhibitor of JAK3 that selectively inhibits JAK3 at an IC50 of 78 µM without altering the activity of JAK1 or JAK2, or any other protein tyrosine kinases (IC50 ≥ 350 µM).
Formula C16H15N3O3
Molecular Weight 297.31
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms WHI-P131
SMILES COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)O)OC
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.