Jak1 cDNA ORF Clone, Rat, In cloning vector - CD BioSciences

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Jak1 cDNA ORF Clone, Rat, In cloning vector

Jak1 cDNA ORF Clone, Rat, In cloning vector

SPD-09406

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1 Unit Online Inquiry
Description
Full length Clone DNA of Rat Janus kinase 1.
Target Information
Species Rat
Target Name Jak1
Gene Abbr. Jak1
Gene ID 84598
Full Name Janus kinase 1
Introduction Members of the Janus family of tyrosine kinases (Jak1, Jak2, Jak3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors. Upon cytokine receptor activation, Jak proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. These associated signaling proteins, such as Stats Shc insulin receptor substrates and focal adhesion kinase (FAK) typically contain SH2 or other phospho-tyrosine-binding domains.
Product Details
Description Full length Clone DNA of Rat Janus kinase 1.
NCBI Ref Seq XM_006238453.1
RefSeq ORF Size 3462 bp
Sequence Information Identical with the Gene Bank Ref. ID sequence except for the point mutations: 267T>C, 1443C>T, 1662T>A and 3285T>C not causing the amino acid variation; 425A>G(K142R), 1908G>C(E636D), 2041A>G(K681E).
Vector pGEM-T Vector
Quality Control The plasmid is confirmed by full-length sequencing.
Storage The lyophilized plasmid can be stored at ambient temperature for three months.
Usage
Sequencing Primers SP6 and T7 or M13-47 and RV-M
Antibiotic in E.coli Ampicillin
Shipping Each tube contains lyophilized plasmid.
Storage The lyophilized plasmid can be stored at ambient temperature for three months.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.