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Itraconazole
SPC-01125
CAS No. 84625-61-6
| Size | Price |
| 100 mg | Online Inquiry |
| 200 mg | Online Inquiry |
| Bulk Size | Online Inquiry |
Hedgehog/Smoothened inhibitor ; P450 (e.g. CYP17) inhibitor ; Hedgehog inhibitor ; Autophagy activator
| Description |
|---|
| Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy. |
| Product Details | |
|---|---|
| CAS No. | CAS No. 84625-61-6 |
| Description | Itraconazole (R 51211) is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy. |
| Formula | C35H38Cl2N8O4 |
| Molecular Weight | 705.65031 |
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
| Synonyms | R 51211 |
| SMILES | CCC(C)N1C(=O)N(C=N1)C2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)OCC5COC(O5)(CN6C=NC=N6)C7=C(C=C(C=C7)Cl)Cl |
| Usage | |
|---|---|
| Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.