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IRS-2 Sandwich ELISA Kit
SPK-00775
| Size | Price |
| 1 X 96T | Online Inquiry |
| 5 X 96T | Online Inquiry |
| 10 X 96T | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | IRS-2 |
| Gene Abbr. | IRS2 |
| Gene ID | 8660 |
| Full Name | insulin receptor substrate 2 |
| Alias | IRS-2 |
| Introduction | Insulin Receptor Substrate 2 (IRS-2) is one of the major substrates of the insulin receptor kinase. In vertebrates, IRS-2 functions as a scaffolding protein to coordinate separate branches of the Insulin/IGF-signaling cascades. IRS-2 is essential for normal nutrient homeostasis because it mediates both peripheral insulin action and the effect of IGF-1 on B-cell growth. Mice lacking IRS-2 fail to maintain sufficient compensatory insulin secretion and develop diabetes as young adults. |
| Product Details | |
|---|---|
| Measurement | Sandwich |
| Usage | |
|---|---|
| Application | ELISA |
| Reactivity | |
| Assay Principle | quantitative |
| Sensitivity | 0.39 pg/mL |
| Detection Range | 1.56 pg/mL - 100 pg/mL |
| Sample Volume | 50-100μL |
| Assay Time | 1-5h |
| Detection Wavelength | 450 nm |
| Precision | Intra-assay Precision (Precision within an assay): CV%<8%. Inter-assay Precision (Precision between assays): CV%<10%. |
| Storage & Handling | |
|---|---|
| Storage Temp. | Store at 2-8°C. Please refer to protocol. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.