Ipatasertib (GDC-0068) - CD BioSciences

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Ipatasertib (GDC-0068)

Ipatasertib (GDC-0068)

SPC-01100

Ipatasertib (GDC-0068)

CAS No. 1001264-89-6

Size Price
10 mM (1 mL in DMSO) Online Inquiry
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10 mg Online Inquiry
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Akt inhibitor

Description
Ipatasertib (GDC-0068, RG7440) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA. Phase 2.
Product Details
CAS No. CAS No. 1001264-89-6
Description Ipatasertib (GDC-0068, RG7440) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA. Phase 2.
Formula C24H32ClN5O2
Molecular Weight 458
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms RG7440
SMILES CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

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