IOX2 - CD BioSciences

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IOX2

IOX2

SPC-01097

IOX2

CAS No. 931398-72-0

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10 mM (1 mL in DMSO) Online Inquiry
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HIF modulator

Description
IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH.
Product Details
CAS No. CAS No. 931398-72-0
Description IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH.
Formula C19H16N2O5
Molecular Weight 352.34
Storage 3 years -20°C powder
2 years -80°C in solvent
Synonyms JICL38
SMILES C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O
Solubility DMSO
Usage
Storage 3 years -20°C powder
2 years -80°C in solvent

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.