Online Inquiry
IOX2
SPC-01097
CAS No. 931398-72-0
Size | Price |
10 mM (1 mL in DMSO) | Online Inquiry |
10 mg | Online Inquiry |
50 mg | Online Inquiry |
Bulk Size | Online Inquiry |
HIF modulator
Description |
---|
IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH. |
Product Details | |
---|---|
CAS No. | CAS No. 931398-72-0 |
Description | IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH. |
Formula | C19H16N2O5 |
Molecular Weight | 352.34 |
Storage | 3 years -20°C powder 2 years -80°C in solvent |
Synonyms | JICL38 |
SMILES | C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=C(C2=O)C(=O)NCC(=O)O)O |
Solubility | DMSO |
Usage | |
---|---|
Storage | 3 years -20°C powder 2 years -80°C in solvent |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.