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Integrin αD/CD11d Antibody
SPA-06177
| Size | Price |
| 0.1 mL | Online Inquiry |
| 25 µL | Online Inquiry |
| More Options | Online Inquiry |
| Target Information | |
|---|---|
| Target Name | Integrin |
| Gene Abbr. | ITGAD |
| Gene ID | 3681 |
| Full Name | integrin subunit alpha D |
| Alias | ADB2, CD11D |
| Introduction | Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling). |
| Product Details | |
|---|---|
| Host | Mouse |
| Clonality | Monoclonal |
| Clone No. | CA11.8H2 |
| Isotype | IgG1 |
| Immunogen | Affinity purified CD11 antigen from canine spleen. |
| Usage | |
|---|---|
| Application | FC, IHC, IP |
| Dilutions | Flow Cytometry (1:10-1:20); Immunohistochemistry (1:10-1:500); Immunoprecipitation (1:10-1:500) |
| Reactivity | Canine |
| Specificity | Recognizes the canine CD11d cell surface antigen (the integrin ad sub-unit). The ad integrin is a newly recognized integrin chain that is expressed as a heterodimer with the b2 integrin (CD18). CD11d is expressed by a sub-population of CD8 positive T cells, macrophages and by gd T cells in the splenic red pulp. |
| Storage & Handling | |
|---|---|
| Storage Buffer | PBS (pH 7.4). |
| Preservative | 0.09% Sodium Azide |
| Storage Temp. | Store at 4 °C for a short term. Aliquot and store at -20 °C for long-term storage. |
| Handling | Avoid freeze-thaw cycles. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.