Integrin β8 Antibody - CD BioSciences

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Integrin β8 Antibody

Integrin β8 Antibody

SPA-06390

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Target Information
Target Name Integrin
Gene Abbr. ITGB8
Gene ID 3696
Full Name integrin subunit beta 8
Introduction Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins having distinct tissue distribution and overlapping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling).
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 416922
Isotype IgG2B
Immunogen Mouse myeloma cell line NS0-derived recombinant human Integrin beta 8. Glu43-Arg684 (predicted). Accession # P26012.
Usage
Application FC
Dilutions Flow Cytometry (0.25 μg/10^6 cells)
Reactivity Human
Specificity Detects human Integrin beta 8 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human Integrins beta 1, beta 2, beta 3, beta 4, beta 5, beta 6, beta 7, or recombinant mouse Integrin beta 8 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.