Integrin α6 Antibody - CD BioSciences

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Integrin α6 Antibody

Integrin α6 Antibody

SPA-06153

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100 µg Online Inquiry
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Target Information
Target Name Integrin
Gene Abbr. ITGA6
Gene ID 3655
Full Name integrin subunit alpha 6
Alias CD49f, ITGA6B, VLA-6
Introduction Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling).Integrin α6 is a 120 kDa protein with two splice variants, integrin α6, 6A and 6B which function as receptors for laminins on the basal membrane to mediate cellular adhesion events. α6 integrins have been shown to play an important role in hematopoietic stem and progenitor cell homing to the bone marrow.
Product Details
Host Rat
Clonality Monoclonal
Clone No. GoH3
Isotype IgG2A Kappa
Immunogen The immunogen for this antibody was CD49f.
Usage
Application FC, IHC, IP
Dilutions Flow Cytometry (1:10-1:1000); Immunohistochemistry (1:10-1:500); Immunoprecipitation (1:10-1:500)
Reactivity Human, Mouse, Bovine
Storage & Handling
Storage Buffer PBS.
Preservative 0.02% Sodium Azide
Storage Temp. Store at 4 °C.
Handling Do not freeze.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.