Integrin α4 Antibody - CD BioSciences

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Integrin α4 Antibody

Integrin α4 Antibody

SPA-06112

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Target Information
Target Name Integrin
Gene Abbr. ITGA4
Gene ID 3676
Full Name integrin subunit alpha 4
Alias CD49D, IA4
Introduction Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling).
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 599904
Isotype IgG1
Immunogen Chinese hamster ovary cell line CHO-derived recombinant human Integrin alpha 4/CD49d. Tyr34-Gln970 (Arg591Leu & Arg878Gln). Accession # P13612.
Usage
Application ELISA
Reactivity Human
Specificity Detects human Integrin alpha 4/CD49d in direct ELISA. In a sandwich immunoassay, this antibody detects the human Integrin alpha 4 beta 1 heterodimer when used with the suggested detection antibody, Mouse Anti-Human Integrin beta 1.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.