Integrin α3/CD49c Antibody - CD BioSciences

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Integrin α3/CD49c Antibody

Integrin α3/CD49c Antibody

SPA-06106

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Target Information
Target Name Integrin
Gene Abbr. ITGA3
Gene ID 3675
Full Name integrin subunit alpha 3
Alias CD49C, FRP-2, GAP-B3, GAPB3, ILNEB
Introduction Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling).
Product Details
Host Goat
Clonality Polyclonal
Clone No. N/A
Isotype IgG
Immunogen S. frugiperda insect ovarian cell line Sf 21-derived recombinant mouse Integrin alpha 3/CD49c. Phe33-Glu993. Accession # Q62470.
Usage
Application WB, FC
Dilutions Western Blot (0.1 µg/mL); Flow Cytometry (0.25 µg/10^6 cells)
Reactivity Mouse
Specificity Detects mouse Integrin alpha 3/CD49c in direct ELISAs and Western Blots. In direct ELISAs, less than 10% cross-reactivity with recombinant human (rh) Integrin alpha 3 is observed.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative No Preservative
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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