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Integrin α3/CD49c Antibody
SPA-06101
Size | Price |
0.1 mL | Online Inquiry |
25 µL | Online Inquiry |
More Options | Online Inquiry |
Target Information | |
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Target Name | Integrin |
Gene Abbr. | ITGA3 |
Gene ID | 3675 |
Full Name | integrin subunit alpha 3 |
Alias | CD49C, FRP-2, GAP-B3, GAPB3, ILNEB |
Introduction | Integrins are α/β heterodimeric cell surface receptors that play a pivotal role in cell adhesion and migration, as well as in growth and survival. The integrin family contains at least 18 α and 8 β subunits that form 24 known integrins with distinct tissue distribution and overlapping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with the extracellular environment (inside-out signaling). |
Product Details | |
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Host | Mouse |
Clonality | Monoclonal |
Clone No. | ASC-1 |
Isotype | IgG1 Kappa |
Immunogen | Human SSC-9 cell line (squamous cell carcinoma). |
Usage | |
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Application | WB, FC, IHC, IP |
Dilutions | Western Blot (1:100-1:2000); Flow Cytometry (1:10-1:1000); Immunohistochemistry (1:10-1:500); Immunoprecipitation (1:10-1:500) |
Reactivity | Human |
Specificity | The antibody HTF-14 recognizes an epitope located in the N-terminal domain of human serum transferrin, a 77 kDa single polypeptide chain glycoprotein (member of the iron binding family of proteins). It is synthesised in the liver and consists of two domains each having a high affinity reversible binding site for Fe3+. |
Storage & Handling | |
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Storage Buffer | PBS (pH 7.4). |
Preservative | 15 mM Sodium Azide |
Storage Temp. | Store at 4 °C. |
Handling | Do not freeze. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.