Insulin Antibody - CD BioSciences

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Insulin Antibody

Insulin Antibody

SPA-06037

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Target Information
Target Name Insulin
Gene Abbr. INS
Gene ID 3630
Full Name insulin
Alias IDDM, IDDM1, IDDM2, ILPR, IRDN
Introduction The maintenance of glucose homeostasis is an essential physiological process that is regulated by hormones. An elevation in blood glucose levels during feeding stimulates insulin release from pancreatic β cells through a glucose sensing pathway. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Insulin stimulates glucose uptake from blood into skeletal muscle and adipose tissue. Insulin deficiency leads to type 1 diabetes mellitus.
Product Details
Host Rabbit
Clonality Monoclonal
Clone No. C27C9
Immunogen Synthetic peptide corresponding to the sequence of human insulin.
Source/Purification Antibody is produced by immunizing animals with a synthetic peptide corresponding to the sequence of human insulin.
Usage
Application IF, IHC, FC
MW(KDa) 6
Reactivity Human, Mouse, Rat
Sensitivity Endogenous
Specificity It detects endogenous levels of total insulin protein.
Storage & Handling
Storage Buffer Supplied in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/mL BSA, 50% glycerol and less than 0.02% sodium azide.
Preservative Less than 0.02% Sodium Azide
Storage Temp. Store at -20 °C.
Handling Do not aliquot the antibody.

For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.