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INS cDNA ORF Clone, Human, In cloning vector
SPD-08729
| Size | Price |
| 1 Unit | Online Inquiry |
| Description |
|---|
| Full length Clone DNA of Human insulin. |
| Target Information | |
|---|---|
| Species | Human |
| Target Name | Insulin |
| Gene Abbr. | INS |
| Gene ID | 3630 |
| Full Name | insulin |
| Alias | IDDM, IDDM1, IDDM2, ILPR, IRDN |
| Introduction | The maintenance of glucose homeostasis is an essential physiological process that is regulated by hormones. An elevation in blood glucose levels during feeding stimulates insulin release from pancreatic β cells through a glucose sensing pathway. Insulin is synthesized as a precursor molecule, proinsulin, which is processed prior to secretion. A- and B-peptides are joined together by a disulfide bond to form insulin, while the central portion of the precursor molecule is cleaved and released as the C-peptide. Insulin stimulates glucose uptake from blood into skeletal muscle and adipose tissue. Insulin deficiency leads to type 1 diabetes mellitus. |
| Product Details | |
|---|---|
| Description | Full length Clone DNA of Human insulin. |
| NCBI Ref Seq | NM_000207.2 |
| RefSeq ORF Size | 333 bp |
| Sequence Information | Identical with the Gene Bank Ref. ID sequence except for the point mutation 6 C/A not causing the amino acid variation. |
| Vector | pMD18-T Simple Vector |
| Quality Control | The plasmid is confirmed by full-length sequencing. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
| Usage | |
|---|---|
| Sequencing Primers | M13-47 and RV-M |
| Antibiotic in E.coli | Ampicillin |
| Shipping | Each tube contains lyophilized plasmid. |
| Storage | The lyophilized plasmid can be stored at ambient temperature for three months. |
For research use only. Not intended for any clinical use. No products from CD BioSciences may be resold, modified for resale or used to manufacture commercial products without prior written approval from CD BioSciences.