Inhibin Antibody - CD BioSciences

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Inhibin Antibody

Inhibin Antibody

SPA-06007

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Target Information
Target Name Inhibin
Gene Abbr. INHA
Gene ID 3623
Full Name inhibin subunit alpha
Introduction Activin and Inhibin are members of the TGF-beta superfamily of cytokines and are involved in a wide range of biological processes including tissue morphogenesis and repair, fibrosis, inflammation, neural development, hematopoiesis, reproductive system function, and carcinogenesis. Activin and Inhibin are produced as precursor proteins. Their amino terminal propeptides are proteolytically cleaved and facilitate formation of disulfide-linked dimers of the bioactive proteins. Activins are nonglycosylated homodimers or heterodimers of various beta subunits ( beta A, beta B, beta C, and beta E in mammals), while Inhibins are heterodimers of a unique alpha subunit and one of the beta subunits. Activin A is a widely expressed homodimer of two beta A chains. The beta A subunit can also heterodimerize with a beta B or beta C subunit to form Activin AB and Activin AC, respectively.
Product Details
Host Mouse
Clonality Monoclonal
Clone No. 130408R
Isotype IgG1
Immunogen Chinese hamster ovary cell line CHO-derived recombinant human Inhibin alpha chain. Accession # P05111.
Usage
Application ELISA
Reactivity Human
Specificity Detects human Inhibin alpha chain in direct ELISAs. In sandwich immunoassays, this antibody captures the human Inhibin alpha chain and detects either human Inhibin A or human Inhibin B based on the detection antibody.
Storage & Handling
Storage Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Storage Temp. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Handling Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

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